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European Collection of Authenticated Cell Cultures
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Gallus BioPharmaceuticals
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Korean Cell Line Bank
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Anticancer Inc
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Charles River Laboratories
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Eppendorf AG
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Servicebio Inc
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North American Biologicals Inc
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Johns Hopkins HealthCare
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Procell Inc
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Image Search Results
a " width="100%" height="100%">
Journal: Analytical Chemistry
Article Title: Mass Spectrometry Analysis of Glycopeptides Enriched by Anion Exchange-Mediated Methods Reveals PolyLacNAc-Extended N -Glycans in Integrins and Tetraspanins in Melanoma Cells
doi: 10.1021/acs.analchem.3c04045
Figure Lengend Snippet: Specificity of Enrichment of PolyLacNAc-Containing Glycopeptide of Anion Exchange Columns from A375 Cell Lysates
Article Snippet: The
Techniques:
Journal: iScience
Article Title: Development of chimeric antigen receptor (CAR)-T cells targeting A56 viral protein implanted by oncolytic virus
doi: 10.1016/j.isci.2024.109256
Figure Lengend Snippet: In vitro and in vivo functionality of A56-specific A56 CAR-T cells (A) Real-time cytotoxicity of A56 CAR-T cells against HCT-116 cells infected with 0.05 MOI of OTS-412. (B) Quantification of A56 CAR-T cell cytotoxicity in various human cancer cell lines infected with OTS-412. (∗∗∗ p < 0.001, comparison of T cell groups; n = 2 for A549, HCT-116, HeLa, SK-MEL-5 and n = 3 for MCF7 and PC-3 by two-tailed unpaired t test). Data are represented as the mean value ± SEM. (C) Aggregation of A56 CAR-T cells targeting tumor cells observed every 12 h until day 4 in real-time. (D) Antigen-dependent anti-tumor efficacy of A56 CAR-T cells in HCT-116 tumor-bearing mice after intratumoral T cell injection following OTS-412 injection with or without HU (∗ p < 0.05, ∗∗ p < 0.01, comparison of T cell groups; saline, n = 5; treatment groups, n = 4, two-way ANOVA with multiple comparison). Data are represented as the mean value ± SD. (E) IHC analysis of A56 expression and infiltrated hCD3 + T cells in tumors isolated from HCT-116 tumor-bearing mice 21 days post-intravenous T cell treatment. Scale bar, 20 μm (left panel) and quantitation of tumor-infiltrating A56 CAR-T cells positive for hCD3 (right panel) (∗ p = 0.01, n = 3, two-tailed unpaired t test). Data are presented as the mean ± SD. MOI, multiplicity of infection; IHC, immunohistochemistry.
Article Snippet: HeLa (cervical carcinoma; ATCC) and
Techniques: In Vitro, In Vivo, Infection, Comparison, Two Tailed Test, Injection, Saline, Expressing, Isolation, Quantitation Assay, Immunohistochemistry